ctlbj ctlbj 祖源分析

新的蒙古族样本

2018年11月5日在Nature Genetics发表的一篇文章对175位来自6个不同部落的蒙古族个体测了全序,并将样本同其他蒙古族样本做了详细的比较。
Whole-genome sequencing of 175 Mongolians uncovers population-specific genetic architecture and gene flow throughout North and East Asia | Haihua Bai, Xiaosen Guo, […]Ye Yin | Nature Genetics | 05 November 2018
Abstract: The genetic variation in Northern Asian populations is currently undersampled. To address this, we generated a new genetic variation reference panel by whole-genome sequencing of 175 ethnic Mongolians, representing six tribes. The cataloged variation in the panel shows strong population stratification among these tribes, which correlates with the diverse demographic histories in the region. Incorporating our results with the 1000 Genomes Project panel identifies derived alleles shared between Finns and Mongolians/Siberians, suggesting that substantial gene flow between northern Eurasian populations has occurred in the past. Furthermore, we highlight that North, East, and Southeast Asian populations are more aligned with each other than these groups are with South Asian and Oceanian populations.
2018-11-12 • IP属地美国
按热门排序    按默认排序

5 个回复

从论坛看帖这个水平而言,蒙古族至少可以再细分3类以上差异比较大的 。
同一天(2018年11 月5日)在Proceedings of the National Academy of Sciences(PNAS)发表的一篇文章报告,研究人员测了从22具在蒙古国库苏古尔(Khövsgöl)省发现的古尸上采的DNA,证实那些古尸都来自东亚人,已有初期牧业的迹象,但仍缺乏乳糖代谢的功能。
Bronze Age population dynamics and the rise of dairy pastoralism on the eastern Eurasian steppe
www.pnas.org | Choongwon Jeong, Shevan Wilkin, Tsend Amgalantugs, Abigail S. Bouwman, William Timothy Treal Taylor, Richard W. Hagan, Sabri Bromage, Soninkhishig Tsolmon, Christian Trachsel, Jonas Grossmann, Judith Littleton, Cheryl A. Makarewicz, John Krigbaum, Marta Burri, Ashley Scott, Ganmaa Davaasambuu, Joshua Wright, Franziska Irmer, Erdene Myagmar, Nicole Boivin, Martine Robbeets, Frank J. Rühli, Johannes Krause, Bruno Frohlich, Jessica Hendy, and Christina WarinnerPNAS published ahead of print November 5, 2018 https://doi.org/10.1073/pnas.1813608115 
Abstract: Recent paleogenomic studies have shown that migrations of Western steppe herders (WSH) beginning in the Eneolithic (ca. 3300–2700 BCE) profoundly transformed the genes and cultures of Europe and central Asia. Compared with Europe, however, the eastern extent of this WSH expansion is not well defined. Here we present genomic and proteomic data from 22 directly dated Late Bronze Age burials putatively associated with early pastoralism in northern Mongolia (ca. 1380–975 BCE). Genome-wide analysis reveals that they are largely descended from a population represented by Early Bronze Age hunter-gatherers in the Baikal region, with only a limited contribution (∼7%) of WSH ancestry. At the same time, however, mass spectrometry analysis of dental calculus provides direct protein evidence of bovine, sheep, and goat milk consumption in seven of nine individuals. No individuals showed molecular evidence of lactase persistence, and only one individual exhibited evidence of >10% WSH ancestry, despite the presence of WSH populations in the nearby Altai-Sayan region for more than a millennium. Unlike the spread of Neolithic farming in Europe and the expansion of Bronze Age pastoralism on the Western steppe, our results indicate that ruminant dairy pastoralism was adopted on the Eastern steppe by local hunter-gatherers through a process of cultural transmission and minimal genetic exchange with outside groups.
元月十号 - 【杜】O-MF2636/外公【崔】T-Y13290/外婆【张】O-F723
倒是测测古代人基因呀 
siauhoo - C2c1a2b2/CTS3385
蒙古人有多重基因来源。
发现与芬兰人有联系,说明欧亚大陆北方在过去有基因交流。
总的来说,北亚 东亚 东南亚之间比较接近,这三者之间的差异小于他们与南亚和大洋洲的差异。

要回复问题请先登录注册