健康风险能否增加酒渣鼻？RSID：rs1800629 附文献

该文献指出：
Rs1800629 polymorphism of of TNF-α gene in
patients with rosacea and conditionally healthy donors Uzbeks,
characterized by wide allelic diversity. Functionally unfavorable
genotype rs1800629*G/A of TNF-α gene significantly contributes
to the formation of rosacea and more associated with erythematous
stage of rosacea. The risk of development of pathology in the presence
of this genotype may be increased more than 3 times, and the
chances of forming erythematous stage of disease when it present
are increased by more than 4.5 times (χ 2=29.7; Р<0.05; OR=4.9;
95%CI 2.704–8.865). At that, wild genotype rs1800629*G/G of
TNF-α gene may be associated with a decreased risk of developing
the disease in carriers of this genotype.
 
不过我查了下我自己的，应该属于低风险型。
然而事实是我和我爸爸，我爷爷都有酒渣鼻，我还是个女的。


 
更多的文献我没有再仔细查，应该还有更多的基因位点数据支持，原文见附件。
 

• role-of-g308a-polymorphism-of-tnf-gene-in-the-formation-of-rosacea_(1).pdf